PROGNOSTIC IMPLICATION OF P27KIP1, SKP2 AND CKS1 EXPRESSION IN RENAL CELL CARCINOMA: A TISSUE MICROARRAY STUDY

Prognostic implication of p27Kip1, Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study

Abstract Background p27Kip1 plays a major role as a negative regulator of the cell cycle.The regulation of p27Kip1 degradation is mediated by its specific ubiquitin ligase subunits S-phase kinase protein (Skp) 2 and cyclin-dependent kinase subunit (Cks) 1.However, little is known regarding the prognostic utility of p27Kip1, Skp2 and Cks1 expression

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Dynamics of ecosystem services along ecological network seascapes

Human societies depend on services provided by ecosystems, from local needs such as clean water and pest control Starches to global services like the ozone layer and the ocean biological pump.Ecosystem services are linked to the states of the ecosystem, which are, in turn, governed by a web of ecological interactions.These interactions, along with

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Stethoscope hygiene: A legal consideration for cardiologists practicing in a new era of infection control (COVID-19)

The stethoscope is a tool cherished by the field of cardiology and ubiquitous throughout medicine.However, little consideration has been given to its safe usage regarding its potential for pathogenic contamination despite thorough evidence that stethoscopes can harbor pathogens that can be transmitted to patients upon contact.The COVID-19 (SARS-COV

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Petrology, Minerals chemistry and Geochemical relationships of the Sheared Gabbro Rocks in Alanah (Beesha) area within Erbil Governorate, NE Iraq

The current research is seeking to identify the petrography, mineralogy and geochemical relationships of Gabbro rocks in Besha area within Erbil Governorate, at the Unstable Shelf in Imbricate Zone.This study aims to determine the origin of the gabbroic rocks and their geochemical relationships.The basic sheared gabbro rocks are exceptional in the

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